A Raybow USA co-authored article “Industrial-scale chemical synthesis of gold nanorods: process optimization and 30 L scale-up toward GMP manufacturing” was recently published in the Journal of Industrial and Engineering Chemistry.

David Perrey, PhD, Group Leader for Raybow USA, explained the work toward the scale-up of the production of gold nanorods.

“Our colleagues at the University of Bologna had a small-scale preparation and were seeking to produce nanoroads in larger quantity, having seen inconsistent results batch-to-batch in their own research. So, our challenge was to implement a more robust process, while also making the nanorods on a significantly larger scale than had been done previously.

“Our team was able to pinpoint the important reaction parameters to give consistent nanorod structures, as shown by the measured longitudinal LSPR.

“I very much enjoyed the collaboration and was very happy we were able to create a robust process to make gold nanorods for a variety of applications and research.”

Link to the article in the Journal of Industrial and Engineering Chemistry: https://www.sciencedirect.com/science/article/pii/S1226086X26000481

Connect with Raybow USA for support with your integrated small-molecule CMC discovery, IND-enabling studies, and GMP manufacturing.

Message Nathaniel Kim, Sherida Johnson, PhD, Matthew Lauer, David Perrey, Tim Miley, Yuening “Nathan” Jiao, or Gary Richoux to initiate a dialogue.

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